Can I use bacon instead of guanciale? Yes. I mean they’re both cured pork, is not like comparing salmon and beef. But there are differences that result in a pretty defined difference in flavor: Bacon: 1. Cut of Meat: Bacon is typically made from pork belly. 2. Preparation: It is cured, often smoked, and then sliced. 3. Flavor: Bacon has a smoky, salty flavor with a crispy texture when cooked. 4. Use: Common in American cuisine, used in breakfast dishes, sandwiches, salads, and as a topping. Guan