Leading up to the game, the Tigers made an announcement on relief pitcher Kyle Finnegan that reads like a promising sign heading into Monday night's game and the rest of the 2025 MLB season. The Astros lead the season series against Detroit 2-1 so far this season after falling to Detroit in the Wild Card round of the 2024 MLB Playoffs.

The Tigers won a pitching duel between Tarik Skubal and Hunter Brown on a bases-loaded walk in the 10th inning on Tuesday.

DETROIT -- The Detroit Tigers will go for a three-game sweep on Wednesday afternoon. The Tigers (75-53) play the Houston Astros (69-57) at 1:10 p.m. at Comerica Park. Infielders Colt Keith, Zach McKinstry and Trey Sweeney; and outfielder Kerry Carpenter will be available off the bench. The full lineup is below.

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Tigers' reliever Will Vest compared the Cy Young contenders matchup to watching Pedro Martinez face Roger Clemens.

The Tigers hammered Houston for six runs in the first inning to set up a 7-2 victory and a series sweep of the AL West leaders.

Houston Astros outfielder Taylor Trammell left Wednesday’s game against the Detroit Tigers on a cart after crashing into the center field fence in the first inning

For the first time since the 1985 season, the Astros have been shut out in three consecutive games after losing in 10 innings Tuesday.