News Medical

Lack of strength in smooth muscle cells leads to malformations of the blood vessels, study shows

The heart pumps blood through the vascular system, supplying cells with oxygen and energy Smooth muscle cells in the vessels finely regulate the blood flow. If they cannot perform their task, ...
News Medical

Mutation in a single non-coding gene found to be the source of multisystemic smooth muscle dysfunction syndrome

A team of investigators from Massachusetts General Hospital (MGH), a founding member of Mass General Brigham (MGB) and Mass General for Children (MGfC) has identified - for the first time - the ...
Science Daily

Rare smooth muscle disorder traced to a single mutation in a non-coding gene

Using whole genome sequencing, researchers identified a single variant in a microRNA gene, MIR145-5p, as the source of multisystemic smooth muscle dysfunction syndrome, which had gone undiagnosed in a ...
Science Daily

Targeting a specific protein in smooth muscle cells may dramatically reduce atherosclerotic plaque formation

A new study shows targeting a protein in smooth muscle cells can block and decrease buildup of atherosclerotic plaque in mouse models, according to researchers. A new study shows targeting a protein ...