Alzheimer's disease (AD) is a highly debilitating neurodegenerative disease characterized by the progressive loss of memory and decline of mental functions. Earlier research has uncovered some of the ...

Disrupted sleep patterns in Alzheimer’s disease may be more than a symptom—they could be a driving force. Researchers at Washington University found that the brain’s circadian rhythms are thrown off ...

The powerful, and often shifty, role that microglia play in Alzheimer’s and other neurodegenerative diseases is a topic of intense study. However, as demonstrated by presentations at the AD/PD meeting ...

Move over, amyloid, reactive astrocytes and activated microglia may be the main drivers of the Alzheimer’s disease pathological cascade. In the November 6 Nature Neuroscience, scientists led by Pedro ...

For decades, depression has been explained to patients as a “chemical imbalance” in the brain, a vague phrase that never ...

For decades, Alzheimer’s research has centered on neurons, the brain cells that die as the disease progresses, and on the ...

Major depressive disorder (MDD) is a mental health condition that negatively affects the mood of a person and causes a loss of interest in activities that were previously associated with happiness. In ...

Astrocytes are star shaped cells that make up around 35% of human brain cells. They were once thought of as cells that simply supported neurons in the central nervous system (CNS). But in recent years ...

The potential effects of astrocyte dysfunction in neurodegenerative diseases are summarized in Figure 2. AD is characterized clinically by cognitive loss in two or more domains, including memory, ...

When we learn a new motor skill—whether mastering a piano passage or refining balance while walking—the brain must reorganize the circuits that control movement. For decades, this process of synaptic ...