During the first 72 hours in particular, extracellular vesicles—nanoparticles enclosed in cell membranes—play a significant role in the embryonic development of zebrafish. This is the result of a ...
Lethal toxicity of metformin on zebrafish during early embryonic development by multi-omics analysis
Metformin is an antidiabetic drug used in type 2 diabetes as well as indicators in polycystic ovary syndrome (PCOS) and cancer. Due to their increase in popularity, high amounts of metformin are being ...
A study led by Prof. Liu Feng from the Institute of Zoology of the Chinese Academy of Sciences has identified a crucial role for the tryptophan-aspartic acid (WD) repeat protein 5 (Wdr5) in ...
Researchers confirm using zebrafish that if a certain gene is not excluded when vertebrate embryos are developing, the notochord will not elongate properly, resulting in a shortened form. Can a single ...
Scientists have uncovered a surprising new way that giant embryonic cells divide—without relying on the classic “purse-string” ring long thought essential for splitting a cell in two. Studying ...
How does a tiny cluster of cells become an embryo with a head, trunk, and tail? And how do thousands of genes coordinate this development? A new imaging method makes it possible to visualize the ...
Hair, nails, and horns, all made up of keratin, are some of the hardest and most resilient structures in animals. Inside zebrafish cells, keratin plays a distinct role, giving them the strength they ...
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