Q: What is porphyria and how is it treated? A: The types of porphyria (cutaneous or acute) occur because of a defect in one of the heme synthesizing enzymes. The protein heme is made in essentially ...

Variegate porphyria (VP) is an autosomal dominant condition that results from the deficiency of protoporphyrinogen oxidase (PPOX, EC 1.3). The build-up of porphyrin precursors delta-aminolevulinic ...

If you've spent the last week binging "Queen Charlotte: A Bridgerton Story" you're likely well-versed in the complicated (and steamy!) love between Queen Charlotte and King George III. But this high ...

Dear Dr. Gott: I am a concerned grandmother writing about my 11-year-old granddaughter. She was diagnosed with porphyria at the age of 2. Her hands and feet start hurting so badly that she has to put ...

Most of the porphyrias are inherited conditions. The genes for all the enzymes in the heme pathway have been identified. Some forms of porphyria result from inheriting one altered gene from one parent ...

Bridgerton spin off Queen Charlotte has sparked viewer's interest in the history that inspired the story. The Netflix series explores the relationship between Queen Charlotte and King George III, and ...

You wouldn’t think that King George III had anything in common with vampires. It is not as if the King, who reigned from 1760 to 1820, believed in the undead rising from their graves to suck the blood ...

Doctors have used a new type of medicine called "gene silencing" to reverse a disease that leaves people in crippling pain. The condition, acute intermittent porphyria, also causes paralysis and is ...

Acute intermittent porphyria (AIP) is an inherited condition that causes a mutation in the gene that produces the oxygen-carrying compound haem in red blood cells. The mutation alone does not trigger ...

The folklore of vampires has inspired horror stories for centuries. But the blood-sucking beings may not have been as otherworldly as we think. For scientists believe an actual medical condition ...