While those are the playoff implications for this Christmas Day slate, one of the other storylines will be the onslaught of injuries at quarterback for an array of these teams suiting up on Thursday. The Commanders, Vikings and Chiefs will all be starting backups, which sort of feels like a lump of coal, but we'll make do.

Some of the site's predictions differ from NFL Week 17 odds and other NFL Week 17 picks for NFL Week 17 games. How correct will the analytics be this week? Click on each game for more NFL Week 17 predictions for that NFL matchup. All times MST. The site allows for the possibility of ties, so the numbers add up to just less than 100%.

On a short week for multiple NFL teams, you're going to get Bleacher Report's Week 17 picks against the spread a day earlier than usual—consider it an early present for the holiday.

Jameson Williams is a solid price at +180 (consider buying down to +160/+165). He’s been targeted on 23% of passes over the last three weeks and is matching St. Brown’s yardage output, yet his TD odds are more than 70 cents longer.

With just two weeks left in the 2025 NFL regular season, only a few playoff spots are still up for grabs. The Steelers need either a win or a Ravens loss in the last two weeks to clinch the AFC North, while the Texans and Packers also have a magic number of one in order to capture playoff spots.

We pick the Cowboys, Lions and Broncos, all favorites by at least a touchdown, to win by double digits Thursday.

Week 17 is also loaded with playoff implications. Teams like the Houston Texans (10-5), Los Angeles Chargers (11-4), Chicago Bears (11-4) and San Francisco 49ers (11-4) are still vying for higher seeds in the AFC and NFC.

The Detroit Lions need to win and also need the Baltimore Ravens to beat the Green Bay Packers this week in order to stay in playoff contention. However, Detroit might be relying on a backup quarterback to save their season.