Nature

Differences in vector-genome processing and illegitimate integration of non-integrating lentiviral vectors

A variety of mutations in lentiviral vector expression systems have been shown to generate a non-integrating phenotype. We studied a novel 12 base-pair U3-long terminal repeats (LTR) integrase (IN) ...
Phys.org

AAV vector integration into CRISPR-induced DNA breaks

To design safe clinical trials, it is crucial to better understand and predict gene editing outcomes in preclinical studies. Bence György and collaborators have shown that adeno-associated viruses ...
Nature

Chromosomal effects of adeno-associated virus vector integration

Adeno-associated virus (AAV) vectors are currently being used in several clinical gene-therapy trials (see the NIH OBA Human Gene Transfer Clinical Trials Database); however, little is known about the ...
irblog.prnewswire.com

MongoDB Announces Integration of MongoDB Atlas Vector Search with Amazon Bedrock to Power Next-Generation Applications on AWS

LAS VEGAS, Nov. 29, 2023 /PRNewswire/ -- MongoDB, Inc. (NASDAQ: MDB) today at AWS re:Invent 2023 announced plans to integrate MongoDB Atlas Vector Search with Amazon Bedrock to enable organizations to ...
irblog.prnewswire.com

Hazelcast Adds Vector Search, Unveils Core Architecture for AI Integration

Hazelcast Platform 5.5 delivers advanced query, compute capabilities to power AI and mission-critical applications PALO ALTO, Calif., July 30, 2024 /PRNewswire/ -- Hazelcast, Inc. is announcing the ...