A new discovery by researchers at the RIKEN Center for Biosystems Dynamics (BDR) in Japan upends decades of assumptions regarding DNA replication. Led by Ichiro Hiratani and colleagues, the ...
In eukaryotic cells, DNA replication is organised both spatially and temporally, as evidenced by the stage-specific spatial distribution of replication foci in the nucleus. Despite the genetic ...
If you are anything like us, whenever you plan a journey, you spend a remarkable amount of time thinking about the start and ...
Cells have evolved careful checks to ensure DNA is copied only once, but how they switch on replication at the right moment ...
The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...
Aneuploidy is relatively common during early mammalian embryogenesis, although the exact frequency is unclear 5,6,7,8. Factors contributing to this include the lack of stringent cell-cycle checkpoints ...
Researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer. Every day, billions of cells in your body ...
Embryonic stem (ES) cells are pluripotent stem cells that can produce all cell types of an organism. ES cells proliferate rapidly and have been thought to experience high levels of intrinsic ...
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