The transmembrane protein claudin-2 mediates paracellular sodium reabsorption in the proximal tubule, but given the versatility of transcellular epithelial transport, the paracellular pathway seems ...

The kidney plays a central role in the regulation of arterial blood pressure. A large body of experimental and physiological evidence indicates that renal control of extracellular volume and renal ...

Rockville, Md. (January 24, 2019)--Lower-than-normal zinc levels may contribute to high blood pressure (hypertension) by altering the way the kidneys handle sodium. The study is published ahead of ...

ACE inhibitors work by interfering with the body's renin-angiotensin-aldosterone system (RAAS). RAAS is a complex system responsible for regulating the body's blood pressure. The kidneys release an ...