Advanced Tools Provide Better Solutions for Critical Aspect of Biologics Development Scaling up biologics production from the bench to clinical and commercial scale is a central consideration of ...

The authors discuss a continuous-flow reactor that avoids parallel channels and enables economic plant setup. This article is part of a special issue on API Development, Formulation, Synthesis and ...

A volume change in bioprocessing changes everything else, which is why scale-up can be so unpredictable. It isn’t easy anticipating which upstream or downstream processes will require special ...

Continuous twin-screw granulation offers several options for increasing production scale. Thermo Fisher Scientific explains factors to consider in scale-up projects for manufacturing oral solid-dosage ...

Process development is the exercise of creating new and improved manufacturing methods, optimizing them in terms of time and financial efficiency while maintaining regulatory compliance and product ...