Chronic wasting disease (CWD) is generally associated with animals. But a new study by researchers from the University of ...

Alzheimer's disease and other neurodegenerative conditions can sometimes feature damaging clumps of tau proteins that have become deformed. Scientists have now synthesized these misshapen entities in ...

Prions are highly robust and infectious proteins, most notable for their central role in bovine spongiform encephalopathy, commonly called mad cow disease. But very little is known about how prions ...

Prions can infect both humans and animals, causing Creutzfeldt-Jakob disease (CJD) in humans, mad cow disease in cattle, and chronic wasting disease in elk and deer. The infectious, misfolded protein ...

Researchers have synthesized the first artificial human prion, a dramatic development in efforts to combat a devastating form of brain disease that has so far eluded treatment and a cure. Case Western ...

The misfolding of proteins and their subsequent deposition as amyloid in peripheral nerves lead to sensory and autonomic neuropathy A new hereditary form of neuropathy, prion protein (PrP) systemic ...

Sporadic CJD (sCJD) Unknown, but widely believed to be due to a spontaneous misfolding of the normal prion protein. Affects mainly people over the age of 60. Common symptoms include ataxia and ...

New research from David Westaway, PhD, of the University of Alberta and Jiri Safar, MD, Case Western Reserve University School of Medicine has uncovered a quality control mechanism in brain cells that ...

Close-up on three ropes and marine knots isolated on white background. Each is photographed separately. Prion diseases are rare but deadly neurodegenerative brain diseases that result from misfolding ...