A retrospective study of fifteen patients found dual interleukin-17 blockade significantly improved Darier disease severity while type 2 cytokine inhibitors failed.
T helper 17 (Th17) cells generate the pro-inflammatory cytokine interleukin-17 (IL17/IL17A). IL17 has been a target for a variety of therapeutic monoclonal antibodies and inhibitors to treat different ...
This retrospective cohort study analysed the effectiveness and survival of patients with psoriasis undergoing therapeutic biologic dose spacing of secukinumab or brodalumab. The analysis included 80 ...
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