In just a few decades, DNA sequencing technologies evolved from slow, manual processes to rapid, automated ones, making ...

Imagine that you want to know the plot of a movie, but you only have access to either the visuals or the sound. With visuals alone, you'll miss all the dialog. With sound alone, you will miss the ...

Traditional bisulfite sequencing damages DNA, while enzyme-based alternatives are inconsistent. A novel methylation analysis method, called UMBS-seq, has been published in Nature Communications.

Researchers from Children's Hospital of Philadelphia (CHOP) developed a new RNA sequencing strategy that can reveal how genetic variants disrupt gene function and improve the diagnosis of rare ...

Alternative polyadenylation (APA) and alternative splicing (AS) are essential post-transcriptional mechanisms that enhance transcriptome diversity and regulate gene expression across various ...

The utilization of molecular oncology assays to assist with diagnosis, classification, prediction of prognosis, and selection of therapy has become ubiquitous in recent years, especially in ...

A new DNA sequencing technique that delivers faster and more accurate bacterial infection diagnoses could be implemented nationwide. The method, developed by the Medicines and Healthcare products ...

DNA-based methods dominate molecular cancer diagnostics but struggle to detect gene fusions and assess splice site consequences. RNA sequencing enables sensitive fusion detection and direct assessment ...

A research team led by the A*STAR Genome Institute of Singapore (A*STAR GIS) have developed a method to accurately and efficiently read DNA containing non-standard bases—a task once thought too ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...

Cyprus has begun using an advanced DNA testing method to identify the remains of Greek Cypriot soldiers and civilians who went missing during the Turkish invasion of 1974 after conventional techniques ...

Cambridge, MA - Traditional bisulfite sequencing damages DNA, while enzyme-based alternatives are inconsistent. A novel methylation analysis method, called UMBS-seq, was published this week in Nature ...