Ischemia reperfusion injury (IRI) is one of the main cause of organ dysfunction after heart attack and solid organ transplantation, and occurs frequently when the new organ comes from a deceased ...

Previous work has shown that gap junction intercellular communication (GJIC) enhances cisplatin (Pt) toxicity in testicular tumor cells but decreases it in non-tumor testicular cells. In this study, ...

Endothelial monolayers have shown the ability to signal each other through gap junctions. Gap junction-mediated cell-cell interactions have been implicated in the modulation of endothelial cell ...

When two cells "talk" to each other, they often do so through tiny channels called electrical synapses. Unlike chemical synapses, these so-called gap junctions enable the direct exchange of ...

In their May 2015 Scientific American article “Cellular Small Talk,”Dale W. Laird, Paul D. Lampe and Ross G. Johnson report on recent discoveries showing that the disruption of cellular structures ...

Zebrafish have a remarkable ability to heal their spinal cord after injury. Now, researchers at Karolinska Institutet have uncovered an important mechanism behind this phenomenon—a finding that could ...

A new study by the University of California, Davis, shows how cells work together to avoid a sudden drop in blood sugar. Understanding these feedback loops could improve the lives of people with ...

Researchers studying a critical stage of pregnancy -- implantation of the embryo in the uterus -- have found a protein that is vital to the growth of new blood vessels that sustain the embryo. Without ...

Neighboring cells exchange molecular information via channels that directly connect them. Disruption of this signaling system can lead to disorders ranging from hearing loss to heart disease Like ...