In 2020, Jennifer Doudna won the Nobel Prize in chemistry for her work on the CRISPR-Cas9 gene-editing technology that allows ...

When we think about cancer risk, it’s natural to wonder, “is it genetic?” The truth is, sometimes it is, but in many cases, cancer develops from a mix of lifestyle, environmental factors, and DNA ...

Mitochondria act as energy factories in cells and have their own, separate DNA. Mutations to mitochondrial DNA (mtDNA) have been observed in cancer, but it has been unclear how these changes might ...

Detection of somatic mutations in cell-free DNA (cfDNA) is challenging due to low variant allele frequencies and extensive DNA degradation. Here we develop a benchmarking strategy using longitudinal ...

A gastrointestinal oncologist told Newsweek that the early-stage findings are a “major step forward” in targeting colon ...

IN THE POPULAR imagination, cancer starts with a mutation in the DNA of a normal cell. That mutation allows the cell to multiply uncontrollably, circumventing the body’s usual quality-control checks.

Colorectal cancer (CRC) remains a leading cause of cancer-related morbidity and mortality worldwide, with early detection critical for improving clinical outcomes. In Denmark’s CRC screening program, ...

A CRISPR system detects rare cancer mutations in blood with single-nucleotide precision, outperforming ddPCR through engineered RNA guides and isothermal amplification. (Nanowerk Spotlight) Hidden ...

Scientists have discovered that a gene normally considered a DNA-protecting "good guy" can become dangerous when cells make too much of it. The gene, EXO1, acts like molecular scissors that help ...

In many aspects of our lives, we find meaning in the order in which events occur. We buy into myths about "middle child syndrome," talk of calm before storms, and consider it strange to start a meal ...

Researchers have found that a genetic mutation associated with a rare group of blood cancers does not always result in ...