In this free webinar, learn how modeling and simulation can help navigate the Animal Rule in drug development. Attendees will gain insight into when the Animal Rule is appropriate to use for drug ...

Suggested Citation: "5 In Vitro Alternatives to Animal Models." National Academies of Sciences, Engineering, and Medicine. 2018. Advancing Disease Modeling in Animal-Based Research in Support of ...

Due to advancements in genetic engineering, small animal models are continuing to change in response to market needs. Model developers strive to better reflect the role of this important asset in both ...

A team of researchers from the University of Exeter and the Max Planck Institute for Evolutionary Anthropology has built a model to show where human-animal interactions are in the best interests of ...

A team from the Research Institute of the McGill University Health Center (The Institute) have created a three-dimensional, ...

For many years, the European Union has pursued a policy aimed at the replacement, reduction and refinement of animal testing ...

CRISPR-Cas9 technology is used to knock out or modify DNA in research mice to study disease phenotypes and develop new treatments. CRISPR mice and rats are offered by Charles River, which uses genetic ...

In 2010, researchers at Harvard University developed the first human organ-on-a-chip model. Since then, researchers have built on existing data to improve these once-unimaginable tools. After its ...

A study published in Nature has shown that the GLP-1 drug semaglutide extended the lifespan of older, healthy mice by ...

Humans cannot be used for toxicity testing so animal models or animal data are needed and required in order to develop assessments for humans. (Thayer) One major drawback of animal research is that ...