A retrospective study of 248 patients found that baseline kidney function and age were the primary determinants of mortality ...

Recent randomized, controlled trials suggest that B-cell-depletion therapy with rituximab effectively induces remission in anti-neutrophil-cytoplasmic-antibody-associated vasculitis but is ineffective ...

This study evaluated the clinical and demographic characteristics of biopsy-proven rapidly progressive glomerulonephritis (RPGN), with histological evidence of renal vasculitis. We focused on five ...

Please provide your email address to receive an email when new articles are posted on . “Today is a momentous day in the history of ChemoCentryx; the culmination of decades of effort aimed at offering ...

Please provide your email address to receive an email when new articles are posted on . Despite an ever-growing array of potential candidate biomarkers for antineutrophil cytoplasmic ...

(HealthDay) -- A genome-wide association study of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis shows a genetic contribution to disease susceptibility, which differs between ...

A data-driven subclassification of antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis has identified five distinct clusters with varying degrees of kidney involvement and systemic ...

Avacopan, which targets a receptor that attracts the cells that cause inflammation, was shown to be more effective at keeping patients in remission for a year than prednisone. A Phase 3 clinical trial ...

In patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis treated with rituximab, risk factors for relapse differed by treatment phase; musculoskeletal involvement was ...

The immune system can become the enemy when mechanisms that are actually protective get out of control. In ANCA-associated vasculitis, excessive inflammatory reactions lead to pulmonary hemorrhages ...

(MENAFN- GetNews) The ANCA Vasculitis clinical trial analysis report delivers important insights into ongoing research of 12+ pipeline ANCA Vasculitis drugs, clinical strategies, upcoming therapeutics ...

A case report describes cavitary Pneumocystis jirovecii pneumonia in a man with advanced HIV whose dual ANCA positivity ...