Bundles of actin filaments also known as ‘actin cables’ or ‘stress fibres’ were found in non-muscle cells more than 40 years ago 3. Soon after, it was shown that myosin (myosin II) forms periodic ...
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Dancing proteins keep cells moving: Redefining the function and role of key factors in actin filament disassembly
Some cells, such as immune cells, are highly mobile—they constantly remodel their shape, migrate toward a wound that needs to be closed or chase down bacteria in the bloodstream. This mobility is ...
Research has uncovered how motor protein myosin, which is responsible for contraction of skeletal muscles, functions also in non-muscle cells to build contractile structures at the inner face of the ...
Researchers at Kanazawa University report in eLife on deciphering the actin structure-dependent preferential cooperative binding of cofilin. The actin filament is a double-stranded helical structure ...
During each heartbeat, cardiac contractility results from calcium-activated sliding of actin thin filaments toward the centers of myosin thick filaments to shorten cellular length. Cardiac ...
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