With Brock Purdy continuing to miss time for the 49ers due to injury, Mac Jones has a great opportunity to maximize his earnings.

Kickoff from NRG Stadium is set for 1 p.m. ET, and the Texans are 1.5-point favorites, according to the latest 49ers vs. Texans odds. The over/under for total points scored is 42. Before you make any Texans vs. 49ers picks, make sure to check out what the SportsLine Projection Model has to say.

San Francisco 49ers tight end Jake Tonges catches a 2-yard touchdown pass on a crossing route from quarterback Mac Jones against the Houston Texans.

The Texans lost to the Seattle Seahawks 27-19 on Monday night even though Anderson scored the first touchdown of his NFL career. Anderson had a strip-sack of quarterback Sam Darnold and recovered the fumble in the end zone.

The similarities are obvious. Daniel Jones, Mayfield, Darnold and Mac Jones were high- or mid-first-rounders, while Smith was an early second-rounder. League executives agreed each player has always possessed the physical skills to start in the NFL, which was indicative of their draft stock.

San Francisco 49ers coach Kyle Shanahan provided an update on quarterback Brock Purdy's injury, while Mac Jones suffered a knee contusion.

San Francisco 49ers quarterback Mac Jones locates tight end George Kittle for a 17-yard sliding grab against the Houston Texans.