With the Crew-10 ISS docking, NASA is looking to March 19 at 4 a.m. EDT, for the departure of the Crew 9 Dragon designated Freedom that launched and docked to the ISS over Sept. 28-29 with NASA astronaut Nick Hague and Russian cosmonaut Aleksandr Gorbunov and two empty seats needed for the return of Wilmore and Williams to Earth.

The Crew-10 astronauts will replace four crew members who have been aboard the ISS for an extended stay—NASA’s Nick Hague, Suni Williams, and Butch Wilmore, along with Roscosm

NASA, JAXA, and Roscosmos astronauts join the ISS after a successful SpaceX Dragon mission, welcomed by Expedition 72 crew.

The Crew-10 mission is a routine part of NASA's crew rotation schedule that ensures continuous scientific research and maintenance at the International Space Station. The Crew-10 mission was launched on March 15 at 7:03PM ET,

Reaching orbit from NASA’s Kennedy Space Center, the newest crew includes NASA’s Anne McClain and Nichole Ayers, both military pilots; and Japan’s Takuya Onishi and Russia’s Kirill Peskov, both former airline pilots. They will spend the next six months at the space station, considered the normal stint, after springing Wilmore and Williams free.

The SpaceX Crew-10 launch is scheduled to take place at 7:48 p.m. EST. The launch will happen at Cape Canaveral at the Kennedy Space Center in Florida. Obviously, spacecraft launches can be delayed for a number of reasons, but assuming there are no technical failures or severe weather changes, the launch should occur before 8:00 p.m. EST.

A launch pad problem has forced a flight delay to replace NASA's two stuck astronauts. The new crew needs to get to the International Space Station before Butch Wilmore and Suni Williams can head home after nine months in orbit.