Experts suggest the U.S. has a strategic opportunity to leverage Iran's weakened position for a nuclear deal after Israel's targeted strikes on Iranian nuclear and military sites.

US is involved in stopping Iranian missile and drone fire; the UK and France are not known to participate, but have signaled they could

Iran conflict could open opportunities for Russia to possibly become a power broker to help end the confrontation.

A statement released by Secretary of State Marco Rubio expressed no solidarity with Israel. The response may reflect a certain irritation with Netanyahu, who, by ordering the strikes, has undermined negotiations with Tehran that Trump relaunched in March.

Republicans and some Democrats offered strong support for Israel’s move, but many Democrats called for de-escalation and warned of the consequences of a broader war.

In Israel, rescue teams combed through rubble of residential buildings destroyed by Iranian missiles, using sniffer dogs and heavy excavators to look for survivors after at least 10 people, including children, were killed, raising the two-day toll to 13.